Showing posts with label menopause.. Show all posts
Showing posts with label menopause.. Show all posts

Tuesday, 28 April 2015

Radio 1

I've been for the first session of radiation to the Monster Boob today. My second hospital appointment of the day - the first being this morning to see the physio for another armpit massage.

The radiotherapy is being carried out at a different hospital to the rest of my treatment as there are only four or five radiotherapy suites in the West Midlands (I can't remember exactly - chemo brain again!).

This means instead of it being a 25 minute walk from my flat, I have to walk to a train station in the city centre and get the train through to the hospital. Every day for three weeks. Bit of a ball ache (or boob ache I guess you could say).

They give you a very fetching gown to wear which makes you feel a little bit like you belong in a downmarket massage parlour.... Here I am sporting said gown:

But first let me take a selfie.....

I look totally shattered due to being sleep deprived by menopause inducing drugs so apologies for that!

Anyway, they take you in to a room and you are faced with a machine that looks a bit like this:


I didn't have to chance to take a photo of the actual radiotherapy machine today, however I will try my best to get a portrait of the beast before my treatment is over.

The 'bed' in front of the machine looks like some sort of space age torture contraption, with 'stirrups' for your arms and head. If you've ever had a smear test - think that. Just for the other end of your body.

The whole process only took about 10 minutes but once again was wholly undignified -  having to lie there half naked with your arms above your head whilst two (very sweet) radiographers measure you up and talk numbers over you. However, my dignity upped and left a long time again - I think the final shreds of it slivered out of the room whilst in was i hospital after my surgery so that's by the by.

So far, the only side effect I've had is a warm boob but I've been told it will probably be next week after a few sessions when I start to experience tiredness and sore skin. 

As cancer treatment goes, this definitely beats having a boob cut off or poison injected in to my veins. However, I don't want to count my chickens just yet. Plenty of time for side effects! 

One down, fourteen to go ........

Friday, 20 March 2015

Menopause, schmenopause...

I had an appointment to see my oncologist on Tuesday to discuss hormone treatment. Because my cancer was oestrogen receptive (basically oestrogen made the bugger grow) they can give me medication to try and prevent a recurrence. I use the word try as there are no guarantees that it will work, but fingers crossed hey?

My surgeon put me on Tamoxifen when I went to get the results of my surgery three weeks ago. Tamoxifen is an anti oestrogen drug which tends to be the standard drug of choice for oestrogen receptive breast cancers. Tamoxifen is a mystical drug - it  works in a way that’s quite complicated and not yet even yet fully understood by medical bods.

Oestrogen positive breast cancer cells have proteins called receptors. When oestrogen comes into contact with the receptors, it fits into them and stimulates the cancer cells to divide so that the tumour grows. Tamoxifen fits into the oestrogen receptor and blocks oestrogen from reaching the cancer cells. This means the cancer either grows more slowly or stops growing altogether. Theoretically.

However, I don't want any oestrogen floating round my body - as little as possible anyway. So i asked to see my oncologist abut ovarian suppression or the 'shutting down' of my ovaries. Little bastards...

To cut a (relatively) long story short, my hormone treatment has been changed to one that is deemed to be stronger than tamoxifen. Studies have shown it to be more effective in preventing recurrence and because I am classed as 'high risk' for recurrence (I really wish oncologists would learn to temper their language sometimes!) it would be of greater benefit to me. Such is my disordered brain at the moment, even though I made the appointment to see the oncologist and I left with the drug combination I wanted, I then panic about the fact that they gave it me and think I need it. Sigh.

The treatment involves a monthly injection of a hormone implant called Zoladex and a daily tablet called Exemestane. Zoladex works by stopping the production of luteinising hormone by the pituitary gland, which in turn leads to a reduction in oestrogen produced by the ovaries. I've essentially been put in to a chemically induced menopause which comes with side effects such as hot flushes, mood changes and weight gain. I'm also now at risk of osteoporosis and can lose up to 12% of my bone density per year.

Exemestane is a member of the drug family called aromatase inhibitors. In women who have gone through the menopause the main source of oestrogen is through the conversion of androgens (sex hormones produced by the adrenal glands) into oestrogens. This is carried out by an enzyme called aromatase. The conversion process is known as aromatisation, and it happens mainly in fat. Exemestane blocks the aromatisation process and reduces the amount of oestrogen in the body.

It isn't given on its own to pre-menopausal women (like me) but because I have now been put in to a menopausal state it is the most effective drug to use.

Zolodex is given by injection in to the stomach. This is the needle they use:

I shit you not.

I was brave. No numbing cream. It hurt. Really hurt.

I'll probably be on this combination for about five years (lets hope I live that long). If I have one every month that is 60 of those beauties in my stomach. But to be honest, if it helps to keep the cancer at bay I'd gladly stick it my eye, never mind my stomach.

So here comes the menopause - I'm already having hot flushes that are such that I want to rip my wig off in public places and stick my head in a freezer. I'll be moaning about how things were not the same as when I was a lass and having a blue rinse next. If I had any hair that is.......